Thrombolytic drug shortage is expected to last until 2024. The manufacturing company is limiting supply to all countries worldwide. Currently, the impact on future drug delivery is still unclear. However, for the month October, drug delivery will be further restricted.

Additionally, the production of Actosolv, mainly used for IV cathether obstruction, has not yet been resumed and will likely become unavailable from January 2023. With the help of Belgian experts, FAGG/AFMPS has released guidance for hospital pharmacists and medical doctors concerning the shortage of thrombolytic drugs. The guideline serves the purpose of making other medical specialities aware of the shortage and restricting the use of thrombolytics for non-urgent indications. Centralisation of hospital stock and monitoring of local usage is highly recommended. With regards to treatment of ischemic stroke, increased use of MRI or CT perfusion imaging isrecommended to avoid treating stroke mimics as much as possible, avoiding off-label alteplase use and optimalisation of alteplase dosing using complete vials of 20 and 50mg, taking into account local availability of both dosages, is advised to avoid wastage.


Read the FAGG recommendation here:

Dutch: https://tinyurl.com/4hf5xvxp

French: https://tinyurl.com/c7av4k4c


Belgian Stroke Council recommendation: 

Avoiding tPA wastage by limiting the use of 2x 50mg vials and rounding to full vial dosages.

As a rule of thumb we suggest:

  • 60 kg: 1 x 50 mg
  • 70 kg: 3 x 20 mg
  • 80 kg: 1 x 20 mg + 1 x 50 mg
  • 90 kg: 4 x 20 mg
  • from 100 kg: 2 x 20 mg + 1 x 50 mg

Store excess or mistakenly opened vials for up to 24 hours in the refrigerator for later use.

Furthermore establish communication with the hospital pharmacy: regularly (at least once a month) evaluate the status of the hospital tPA stocks and if necessary, adjust the dose schedule in function of the stocks.


Read also the ESO communication:  



Voor de 2022 editie van Wereld Beroertedag organiseren verschillende ziekenhuizen regionale wandelingen, met de steun van de Belgian Stroke Council. Dit initiatief heet “FAST 4-ward”. Via de app izi.TRAVEL kunnen deze wandelingen worden gedownload en gevolgd.

We voorzien kortere, vaak rolstoeltoegankelijke wandelingen voor minder mobiele mensen, en langere versies.

Klik hier voor meer informatie over de FAST4-ward wandelingen

Covid persbericht

Covid persbericht

AVC et COVID-19.

Comme dans la plupart des pays affectés par l’épidémie de Coronavirus, nous constatons que beaucoup de patients ne se rendent pas à l’hôpital en cas de signe d’AVC, ou s’y rendent trop tard pour bénéficier du meilleur traitement. 

Nous avons donc rédigé un communiqué qui précise que les soins de l’AVC sont garantis pour tous et que, même en période de virus, « time is brain » : en venant vite à l’hôpital, on limite significativement les séquelles et le risque de récidive de l’AVC. Nous attirons aussi l’attention sur le risque accru que courent les personnes isolées et plaidons pour un renforcement des contacts.